… (EBF1) to promote transformation of LMP1-expressing B cells by … EBV EBNA3A phenocopies
EBF1 activities in LMP1-… LMP1 constitutively activates the IKK signaling cascade, while Rel …

… and LMP1 have been shown to be essential for the in-vitro … , which, when depleted, partially
phenocopied EBNA1 depletion by … LMP1 has many functional similarities to a constitutively …

… of immortalization and growth-transformation of B cells infected in vitro. The work … LMP1
and LMP2A are viral homologues of CD40 and BCR, respectively. LMP1 signals constitutively …

… The LMP1 is a main oncogene encoded by EBV that initiates … miR-BART target mRNAs to
phenocopy their antiapoptotic effect in … validation in both in vitro and in vivo. The advantages of …

… constitutively through NF-κB and is required for proliferation … with delayed upregulation of
LMP1/NF-κB signaling in LCLs, … that an in vitro EBV infection of B cells phenocopies several …

… The ability of EBV infection to phenocopy elements of the … LMP1, which mediates CD40
signaling, and LMP2A, which downregulates MHC class II expression and mimics a constitutively …

… inhibit the function of TRAF3 lead to constitutively active NF-… LMP1 is an oncoprotein expressed
by the Epstein Barr virus (… mammalian cells, using in vitro co-immunoprecipitation assays…

… , LMP1 expression in LCLs leads to constitutive activation of … with delayed upregulation of
LMP1/NFκB signaling in LCLs, … that an in vitro EBV infection of B cells phenocopies several …

… Another more recent phenocopy of APDS has been called … This constitutive complex remains
stable due to tight binding … LMP1 in particular is sufficient to transform several cell types, …

… , LMP1 drives oncogenic growth by acting as a constitutive CD40 mimic and activating NFκB
signaling, … Given their established roles in tumor development both in vitro and in vivo, we …